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HRID 1468013作成日：2026年10月27日

5-(Methanesulfonyl)-2,3-dihydro-1H-indole → tert-Butyl-4-(4-(5-(methylsulfonyl)indolin-1-yl)phenoxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468013

反応式

関与物質

役割名称HCID仕込み量
反応物5-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 2736136—
反応物1-BOC-4-(4-bromophenoxy)piperidineHCID 46739006—
生成物tert-Butyl-4-(4-(5-(methylsulfonyl)indolin-1-yl)phenoxy)piperidine-1-carboxylateHCID 67608798—

反応手順

The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl-4-(4-bromophenoxy)piperidine-1-carboxylate and 5-(methylsulfonyl)indoline (0.11 g, 35%); MS: 373 (M−100).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09000175B2
出典データセットuspto-grants-2015_04
ORD IDord-4d6807a380ac49bb82f1befc55ad4d2a
出典メモuspto-grants-2015_04