2-Bromoethyl methyl ether → 3-(2-methoxyethyl)-5-(2,2,2-trifluoroethyl)thiazol-2(3H)-imine hydrobromide
反応式
[F:1][C:2]([F:11])([F:10])[CH2:3][C:4]1[S:8][C:7]([NH2:9])=[N:6][CH:5]=1.[CH3:12][O:13][CH2:14][CH2:15][Br:16]>>[BrH:16].[CH3:12][O:13][CH2:14][CH2:15][N:6]1[CH:5]=[C:4]([CH2:3][C:2]([F:1])([F:10])[F:11])[S:8][C:7]1=[NH:9]参加物
3
実験手順
A mixture of Example 139A and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 241 (M+H)+.
出典と根拠
- ORDレコード
- ord-78f64af53d2d4951a102fc80c6fed69e
- 出典データセット
- uspto-grants-2015_04
- 特許番号
- US09006275B2
反応ノート
読み込み中…