Sulfuric Acid → 7-nitro-2,3-dihydro-1H-indole-2,3-dione
反応式
ON=[CH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14])=[O:5].S(=O)(=O)(O)[OH:17]>>[N+:13]([C:8]1[CH:9]=[CH:10][CH:11]=[C:12]2[C:7]=1[NH:6][C:4](=[O:5])[C:3]2=[O:17])([O-:15])=[O:14]参加物
3
実験手順
2-Hydroxyimino-N-(2-nitro-phenyl)-acetamide (15 g, 72 mmol) was carefully added in small portions over a period of 30 min to a stirred solution of conc. sulphuric acid (45 mL) which was preheated to 90° C. The reaction mixture was stirred for another 2 h at the same temperature then cooled to room temperature, poured into crushed ice. The precipitated products were collected by filtrations, washed with water and dried in a vacuum oven to get 9 g (65%) of brick red colour powder.
後処理
- customwas preheated to 90° C
- additionpoured
- custominto crushed ice
- filtrationThe precipitated products were collected by filtrations
- washwashed with water
- customdried in a vacuum oven
- customto get 9 g (65%) of brick red colour powder
出典と根拠
- ORDレコード
- ord-1ddca985c1a64c9490e2e026a5c7ed3b
- 出典データセット
- uspto-grants-2015_04
- 特許番号
- US09006454B2
反応ノート
読み込み中…