Dimethyl Sulfoxide → 3-{3-Cyano-6-[(2,2-dimethyl-propyl)-amino]-5-fluoro-pyridin-2-ylamino}-N-methoxy-4-methyl-benzamide

反応式

[CH3:32][S:33]([CH3:34])=[O:35].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:16])[c:8]([NH:10][CH2:11][C:12]([CH3:13])([CH3:14])[CH3:15])[n:9]1.[F-:30].[K+:31].[NH2:17][c:18]1[cH:19][c:20]([C:21](=[O:22])[NH:23][O:24][CH3:25])[cH:26][cH:27][c:28]1[CH3:29]>>[c:2]1([NH:17][c:18]2[cH:19][c:20]([C:21](=[O:22])[NH:23][O:24][CH3:25])[cH:26][cH:27][c:28]2[CH3:29])[c:3]([C:4]#[N:5])[cH:6][c:7]([F:16])[c:8]([NH:10][CH2:11][C:12]([CH3:13])([CH3:14])[CH3:15])[n:9]1