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Isoflurane → Isopropyl Myristate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isoflurane | HCID 3763 | — |
| 反応物 | Ketamine | HCID 3821 | — |
| 反応物 | Xylazine | HCID 5707 | — |
| 反応物 | Fluasterone | HCID 133967 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Isopropyl Myristate | HCID 8042 | — |
| 生成物 | (+)-Limonene | HCID 440917 | — |
反応手順
The mice were anesthetized with Isoflurane, and then were given an intramuscular injection of 0.1 mL solution of ketamine (50 mg/kg) and xylazine (10 mg/kg). Approximately 10 minutes after the i.m. injection (after the mice could not turn over when placed on their backs), the mice were treated with 3.7 μL of a mg/mL fluasterone:ethanol:limonene:isopropyl myristate solution to give a dose of 1.5 mg/kg. The mice were anesthetized and on their backs for approximately 30 minutes after application of fluasterone:ethanol:limonene:isopropyl myristate solution. One hour after the application of fluasterone solution, 2 μg of TPA dissolved in 0.2 mL of acetone was applied to the shaved area on the back of each mouse.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09402853B2 |
| 出典データセット | uspto-grants-2016_08 |
| ORD ID | ord-ed89a4e5c5c349d4a59969aedb35f484 |
| 出典メモ | uspto-grants-2016_08 |