HCID 70583868、化合物 → HCID 70562272、化合物
反応式
C(OC([NH:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[CH:12][N:13]2[C:18]([C:26]1[CH:31]=[CH:30][C:29]([Cl:32])=[CH:28][CH:27]=1)([CH2:23][CH2:24][F:25])[C:19]([O:21][CH3:22])=[O:20])=O)(C)(C)C>Cl.CO>[NH2:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[CH:12][N:13]2[C:18]([C:26]1[CH:27]=[CH:28][C:29]([Cl:32])=[CH:30][CH:31]=1)([CH2:23][CH2:24][F:25])[C:19]([O:21][CH3:22])=[O:20]参加物
3
実験手順
A mixture of the product from Step A (100 mg, 0.217 mmol) and 4 N HCl/MeOH (10 mL) was stirred at room temperature for 2 h. After removing the solvent, the residue was dried in vacuo to afford the title compound as brown oil. LC/MS m/z=361.1[M+H]+.
後処理
- customAfter removing the solvent
- customthe residue was dried in vacuo
出典と根拠
- ORDレコード
- ord-784c3850ba9143688a31ff7f3afb16d8
- 出典データセット
- uspto-grants-2016_08