Ethyl trifluoroacetate → 12-Trifluoroacetamidododecanol
反応式
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14].C([O:17][C:18](=O)[C:19]([F:22])([F:21])[F:20])C>C(O)C>[F:20][C:19]([F:22])([F:21])[C:18]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14])=[O:17]参加物
4
実験手順
An ethanol solution (100 ml) of 12-aminododecanol (4.81 g, 23.9 mmol) and trifluoroacetic acid ethyl ester (6.79 g, 47.8 mmol) was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure to give 12-trifluoroacetamidododecanol (1) (6.98 g, q.) as a colorless syrup.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-18304123fc9a41c1bd0a0ee8e098ed8f
- 出典データセット
- uspto-grants-2016_08
- 特許番号
- US09404108B2
反応ノート
読み込み中…