関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | tert-Butyl carbamate | HCID 77922 | — |
| 反応物 | 2,6-Dichloroisonicotinic acid | HCID 94830 | — |
| 試薬 | Potassium Phosphate, Tribasic | HCID 62657 | — |
| 触媒 | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| 触媒 | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid | HCID 72212052 | 0% |
反応手順
Reagents were mixed in a 25 mL round bottom flask and flushed well with nitrogen - heated at 100 °C for 16 h. The mixture looked dark black. Could not detect any starting material or product! It was discarded.
情報源と証拠
| 出典データセット | 750 AstraZeneca ELN dataset |
|---|
| ORD ID | ord-7c9ead47a3324fac997f2b8af6afca02 |
|---|
| 出典メモ | 750 AstraZeneca ELN dataset |
|---|
