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HRID 1480041作成日：2026年10月27日

(S)-alpha-amino-cyclopropanepropanamide → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide

https://huagongshe.com/reaction/1480041

反応式

関与物質

役割名称HCID仕込み量
反応物(S)-alpha-amino-cyclopropanepropanamideHCID 53964035—
反応物5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203638—
生成物5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amideHCID 76281995—

反応手順

The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and (S)-α-amino-cyclopropanepropanamide (CAN 156077-93-9) as starting materials and isolated (18 mg, 53%) as white solid; MS (ESI, m/z): 338.3 (MH+).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09409866B2
出典データセットuspto-grants-2016_08
ORD IDord-a68796482c844af2a52e2b4a12bc455c
出典メモuspto-grants-2016_08