化工社化工社 化学情報印刷レポート · 研究参考用
2-Amino-2-methylpropionitrile → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (cyano-dimethyl-methyl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-2-methylpropionitrile | HCID 88022 | — |
| 反応物 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203638 | — |
| 生成物 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (cyano-dimethyl-methyl)-amide | HCID 76282718 | — |
反応手順
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and 2-amino-2-methyl-propanenitrile (CAN 19355-69-2 as starting materials and isolated (50 mg, 78%) as colorless oil; LC-MS (UV peak area, m/z) 93.8%, 294.1001 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09409866B2 |
| 出典データセット | uspto-grants-2016_08 |
| ORD ID | ord-116c0f1a1d25480890d20d308903682a |
| 出典メモ | uspto-grants-2016_08 |