Hydrochloric Acid → HCID 178483276、化合物
反応式
[CH3:1][N:2]([CH2:10][CH2:11][CH:12]1[CH2:17][CH2:16][N:15](C(OC(C)(C)C)=O)[CH2:14][CH2:13]1)[C:3]([C:5]1[N:6]=[N:7][NH:8][CH:9]=1)=[O:4].Cl.O1CCOCC1>CCOC(C)=O>[CH3:1][N:2]([CH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1)[C:3]([C:5]1[N:6]=[N:7][NH:8][CH:9]=1)=[O:4]参加物
5
実験手順
To tert-butyl 4-(2-(N-methyl-1H-1,2,3-triazole-4-carboxamido)ethyl)piperidine-1-carboxylate (step 2) (190 mg, 0.563 mmol) in EtOAc (5 ml) was added 4N HCl in dioxane (5 ml, 20.00 mmol). The mixture was stirred for 30 mins and concentrated under reduced pressure to give crude N-methyl-N-(2-(piperidin-4-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide as a gum. This was used in the next step without further purification.
後処理
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-8058b4b6dee845188f043dfeccfb93b0
- 出典データセット
- uspto-grants-2016_08
- 特許番号
- US09409895B2
反応ノート
読み込み中…