化工社化工社 化学情報印刷レポート · 研究参考用
Benzoyl chloride → (3-Benzoylamino-propyl)-carbamic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | tert-Butyl (3-aminopropyl)carbamate | HCID 2735700 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | (3-Benzoylamino-propyl)-carbamic acid tert-butyl ester | HCID 10492863 | — |
反応手順
(3-Amino-propyl)-carbamic acid tert-butyl ester (1.6 g) was treated with with benzoyl choride (1.1 eq.) and triethylamine (1.5 eq) in methylene chloride (50 mL). The reaction mixture was washed with 1 N HCl, sat, NaHCO3, and sat NaCl and the solvent removed to give product. LC-MS showed the product had the expected M+H+ of 279.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732444B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-28cac14ad73544c99a6be09cbbe020e9 |
| 出典メモ | uspto-grants-2010_06 |