HCID 68290880、化合物 → HCID 73387062、化合物
反応式
FC(F)(F)S(O[C:7]1[N:8]=[CH:9][C:10]2[C:15]([CH:16]=1)=[C:14]([NH:17][CH2:18][CH:19]1[CH2:21][CH2:20]1)[N:13]=[CH:12][CH:11]=2)(=O)=O.[CH3:24][O:25][C:26]1[CH:32]=[C:31]([C:33]2[CH:34]=[N:35][N:36]([CH3:38])[CH:37]=2)[CH:30]=[CH:29][C:27]=1[NH2:28]>>[CH:19]1([CH2:18][NH:17][C:14]2[C:15]3[C:10](=[CH:9][N:8]=[C:7]([NH:28][C:27]4[CH:29]=[CH:30][C:31]([C:33]5[CH:34]=[N:35][N:36]([CH3:38])[CH:37]=5)=[CH:32][C:26]=4[O:25][CH3:24])[CH:16]=3)[CH:11]=[CH:12][N:13]=2)[CH2:21][CH2:20]1参加物
3
実験手順
The title compound was prepared according to Method 6 (Example 103) using 5-((cyclopropylmethyl)amino)-2,6-naphthyridin-3-yl trifluoromethanesulfonate (Preparation 96) and 2-methoxy-4-(1-methyl-1H-pyrazol-4-yl)aniline (Preparation 19) for 3 hours. The residue was purified using silica gel column chromatography eluting with 0-10% MeOH in DCM.
後処理
- customfor 3 hours
- customThe residue was purified
- washeluting with 0-10% MeOH in DCM
出典と根拠
- ORDレコード
- ord-a06ce586230e46b68b025e37f36d4575
- 出典データセット