化工社化工社 化学情報印刷レポート · 研究参考用
tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate → 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate | HCID 2756485 | — |
| 反応物 | 3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde | HCID 24901965 | — |
| 生成物 | 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester | HCID 86603279 | — |
反応手順
Intermediate 1 was coupled with 3-Aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product had the expected M+H+ of 403.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732444B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-90a6330773f14fc6afd87a1a5c12a5a6 |
| 出典メモ | uspto-grants-2010_06 |