HCID 2800167、化合物 → HCID 118021320、化合物
反応式
CC1C(C)=CC=CC=1OC1N=CC(N)=CC=1.[CH3:17][CH:18]([C:20]1[CH:21]=[C:22]([O:26][C:27]2[N:32]=[CH:31][C:30]([NH2:33])=[CH:29][CH:28]=2)[CH:23]=[CH:24][CH:25]=1)[CH3:19].C[O:35][C:36]([NH:38][N:39]=[CH:40]OC)=O>>[CH3:19][CH:18]([C:20]1[CH:21]=[C:22]([O:26][C:27]2[N:32]=[CH:31][C:30]([N:33]3[CH:40]=[N:39][NH:38][C:36]3=[O:35])=[CH:29][CH:28]=2)[CH:23]=[CH:24][CH:25]=1)[CH3:17]参加物
4
実験手順
The title compound was prepared in a similar way with respect to Example 50 replacing 6-[(2,3-dimethylphenyl)oxy]-3-pyridinamine with 6-{[3-(1-methylethyl)phenyl]oxy}-3-pyridinamine and methyl (2E/Z)-2-(1-methoxyethylidene)hydrazinecarboxylate (Intermediate 21) with methyl-2-[1-(methyloxy)methylidene]hydrazinecarboxylate (Intermediate 28). The title compound, 21 mg, was obtained by preparative HPLC.
出典と根拠
- ORDレコード
- ord-627e46ef42064ad1a7167c8c83d1385c
- 出典データセット