化工社化工社 化学情報印刷レポート · 研究参考用
Nitromethane → 2-Fluoro-1-methoxy-4-(2-nitro-vinyl)benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nitromethane | HCID 6375 | — |
| 反応物 | 3-Fluoro-p-anisaldehyde | HCID 67696 | — |
| 反応物 | Ammonium Acetate | HCID 517165 | — |
| 生成物 | 2-Fluoro-1-methoxy-4-(2-nitro-vinyl)benzene | HCID 53414639 | — |
反応手順
3-Fluoro-4-methoxy-benzaldehyde (10 g) was dissolved in 100 mL of nitromethane along with 5 g of ammonium acetate. The mixture was refluxed for 2 hours. The nitromethane was removed by rotary evaporation and the residue recrystallized from ethanol to give 7.6 g of the expected product. LC-MS showed the product had the expected M+H+ of 198.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732444B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-9fee8e75ba3d4258a595d0347fb4ef58 |
| 出典メモ | uspto-grants-2010_06 |