化工社化工社 化学情報印刷レポート · 研究参考用
Water → 1-Acridinamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 9-Isothiocyanatoacridine | HCID 82090 | — |
| 反応物 | Gentamicin Sulfate | HCID 9855350 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 1-Acridinamine | HCID 11352 | 910.6% |
反応手順
9-Isothiocyanatoacridin (100 mg) was dissolved in MeOH (5 mL), and added to the solution of gentamicin sulfate (250 mg) in 5 mL MeOH and some drops of water, followed by the solution of BaO (100 mg) in 5 mL MeOH. The suspension was stirred 30 min, neutralized with 3% H2SO4 in MeOH, filtered, evaporated to dryness and the residue was washed carefully with dichloromethane. Obtained 297 mg of yellow powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09427406B2 |
| 出典データセット | uspto-grants-2016_08 |
| ORD ID | ord-5a66c58179864bdf88f5c0b726aeec75 |
| 出典メモ | uspto-grants-2016_08 |