4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → 7-(Piperidin-4-yl)imidazo[1,5-a]pyridine hydrochloride

HRID 1487891ノート

反応式

HRID 1487891 の反応式
[ClH:1].N1CCC(C2C=CC(C#N)=CC=2)CC1.[CH:16]1[N:17]=[CH:18][N:19]2[CH:24]=[CH:23][C:22]([CH:25]3[CH2:30][CH2:29][N:28](C(OC(C)(C)C)=O)[CH2:27][CH2:26]3)=[CH:21][C:20]=12.C(C1C=CC(C2CCN(C(OC(C)(C)C)=O)CC2)=CC=1)#N>>[ClH:1].[NH:28]1[CH2:27][CH2:26][CH:25]([C:22]2[CH:23]=[CH:24][N:19]3[CH:18]=[N:17][CH:16]=[C:20]3[CH:21]=2)[CH2:30][CH2:29]1

参加物

4

反応物 3

HCID 193916184-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1)HCID 22492960Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylateHCID 90033879Tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate2 回

生成物 1

HCID 900290287-(Piperidin-4-yl)imidazo[1,5-a]pyridine hydrochloride

実験手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.2, except tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate (compound 39.4) was used in place of tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate (compound 1.1).

出典と根拠

ORDレコード
ord-76434c922c594439b8f4571607c78cc7
出典データセット
uspto-grants-2016_08
特許番号
US09428502B2

反応ノート

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