Methyl 4-cyclopropyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoate → Methyl 4-cyclobutyl-2-methyl-5-(5-methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)benzoate
反応式
[CH:1]1([C:4]2[C:13]([C:14]3[NH:23][C:17]4[CH2:18][N:19]([CH3:22])[CH2:20][CH2:21][C:16]=4[N:15]=3)=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([CH3:24])[CH:5]=2)[CH2:3][CH2:2]1.[CH:25]1(C2C(C=O)=CC(C(OC)=O)=C(C)C=2)CCC1.C1(C2C(C=O)=CC(C(OC)=O)=C(C)C=2)CC1>>[CH:1]1([C:4]2[C:13]([C:14]3[NH:23][C:17]4[CH2:18][N:19]([CH3:22])[CH2:20][CH2:21][C:16]=4[N:15]=3)=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([CH3:24])[CH:5]=2)[CH2:3][CH2:25][CH2:2]1参加物
4
反応物 3
生成物 1
実験手順
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 87.4, except methyl 4-cyclobutyl-5-formyl-2-methylbenzoate (compound 82.5) was used in place of methyl 4-cyclopropyl-5-formyl-2-methylbenzoate (compound 87.1).
出典と根拠
- ORDレコード
- ord-e4263633a74c4e03834c0638e0275cfa
- 出典データセット
- uspto-grants-2016_08
- 特許番号
- US09428502B2
反応ノート
読み込み中…