HCID 178432711、化合物 → 4-Cyclopropyl-5-(5-methoxy-1H-1,2,4-triazol-3-yl)-2-methylbenzoic acid

HRID 1487988ノート

反応式

HRID 1487988 の反応式
CC1NC(C2C=C(C=CC=2C)C(O)=O)=C(C)N=1.[CH:18]1([C:21]2[C:30]([C:31]3[NH:35][C:34]([O:36][CH3:37])=[N:33][N:32]=3)=[CH:29][C:24]([C:25]([O:27]C)=[O:26])=[C:23]([CH3:38])[CH:22]=2)[CH2:20][CH2:19]1.CC1NC(C2C=C(C=CC=2C)C(OC)=O)=C(C)N=1>>[CH:18]1([C:21]2[C:30]([C:31]3[NH:35][C:34]([O:36][CH3:37])=[N:33][N:32]=3)=[CH:29][C:24]([C:25]([OH:27])=[O:26])=[C:23]([CH3:38])[CH:22]=2)[CH2:19][CH2:20]1

参加物

4

反応物 3

HCID 178432711HCID 178432711、化合物HCID 178497405HCID 178497405、化合物2 回HCID 178497719HCID 178497719、化合物

生成物 1

HCID 1784943084-Cyclopropyl-5-(5-methoxy-1H-1,2,4-triazol-3-yl)-2-methylbenzoic acid

実験手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.7, except methyl 4-cyclopropyl-5-(5-methoxy-4H-1,2,4-triazol-3-yl)-2-methylbenzoate (compound 91.5) was used in place of methyl 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoate (compound 5.6). m/z (ES+) 274 (M+H)+.

出典と根拠

ORDレコード
ord-4c28ee423f024851aa709d58cad28e95
出典データセット
uspto-grants-2016_08
特許番号
US09428502B2

反応ノート

読み込み中…