HCID 178421678、化合物 → 5-Iodo-2-(3-methyloxetan-3-yl)-1H-imidazole-4-carbonitrile

HRID 1488082ノート

反応式

HRID 1488082 の反応式
CC1[NH:3]C=C(C#N)N=1.[I:9][C:10]1[NH:14][C:13]([C:15]2([CH3:19])[CH2:18][O:17][CH2:16]2)=[N:12][C:11]=1[C:20](F)(F)F.CC1NC=C(C(F)(F)F)N=1>>[I:9][C:10]1[NH:14][C:13]([C:15]2([CH3:19])[CH2:18][O:17][CH2:16]2)=[N:12][C:11]=1[C:20]#[N:3]

参加物

4

反応物 3

HCID 178421678HCID 178421678、化合物2 回HCID 178432834HCID 178432834、化合物HCID 178432957HCID 178432957、化合物

生成物 1

HCID 900302075-Iodo-2-(3-methyloxetan-3-yl)-1H-imidazole-4-carbonitrile

実験手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 16.3, except 5-iodo-2-(3-methyloxetan-3-yl)-4-(trifluoromethyl)-1H-imidazole (compound 202.2) was used in place of 2-methyl-4-(trifluoromethyl)-1H-imidazole (compound 16.2). m/z (ES+) 290 (M+H)+.

出典と根拠

ORDレコード
ord-501f88da3944487088cf29b35183af45
出典データセット
uspto-grants-2016_08
特許番号
US09428502B2

反応ノート

読み込み中…