4,4,4-Trifluorobutan-2-one → 4,4,4-Trifluoro-2-oxobutanal

HRID 1488232ノート

反応式

HRID 1488232 の反応式
CC(O)=[O:3].O.[F:6][C:7]([F:13])([F:12])[CH2:8][C:9](=[O:11])[CH3:10]>O1CCOCC1>[F:6][C:7]([F:13])([F:12])[CH2:8][C:9](=[O:11])[CH:10]=[O:3]

参加物

4

反応物 2

HCID 5390014,4,4-Trifluorobutan-2-oneHCID 21899381Acetic acid--water (1/1)

生成物 1

HCID 900219564,4,4-Trifluoro-2-oxobutanal

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

反応条件

温度
100 °C

実験手順

To a solution of SeO2 (4.23 g, 38.1 mmol) in dioxane (25 mL) was added AcOH/H2O (1 mL/1 mL). 4,4,4-Trifluorobutan-2-one (3.81 mL, 31.7 mmol) was added dropwise to the above reaction mixture. The resulting solution was stirred overnight at 100° C. The solution was used in the next step without any further work-up or purification.

後処理

  1. customThe solution was used in the next step without any further work-up or purification

出典と根拠

ORDレコード
ord-ffba34d1e2674065bd8c7ade01904ce5
出典データセット
uspto-grants-2016_08
特許番号
US09428502B2

反応ノート

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