Potassium Hydroxide → 6-Nitro-7-(3-nitro-4-oxo-4H-pyridin-1-yl-)-1,4-dihydroquinoxaline-2,3-dione

HRID 1488969

反応式

F[C:2]1[CH:11]=[C:10]2[C:5]([NH:6][C:7](=[O:13])[C:8](=[O:12])[NH:9]2)=[CH:4][C:3]=1[N+:14]([O-:16])=[O:15].[OH:17][C:18]1[CH:23]=[CH:22][N:21]=[CH:20][C:19]=1[N+:24]([O-:26])=[O:25].[OH-].[K+]>CS(C)=O>[N+:14]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:2]=1[N:21]1[CH:22]=[CH:23][C:18](=[O:17])[C:19]([N+:24]([O-:26])=[O:25])=[CH:20]1)[NH:9][C:8](=[O:12])[C:7](=[O:13])[NH:6]2)([O-:16])=[O:15]

参加物

実験手順

First, 677 mg of 7-fluoro-6-nitro-1,4-dihydroquinoxaline-2,3-dione, 840 mg of 4-hydroxy-3-nitropyridine, 403 mg of powdered potassium hydroxide were added to 6 ml of dry dimethylsulfoxide. The mixture was allowed to react at 130° C. for 2 hours in a nitrogen atmosphere. The subsequent processes were conducted in the same way as in Example 2. The resultant precipitate was recrystallized with dimethylformaldehyde and water, giving 672 mg of red crystals of 6-nitro-7-(3-nitro-4-oxo-4H-pyridin-1-yl)-1,4-dihydroquinoxaline-2,3-dione

後処理

customto react at 130° C. for 2 hours in a nitrogen atmosphere
customThe resultant precipitate was recrystallized with dimethylformaldehyde and water

出典と根拠

ORDレコード: ord-ff3d3872a8f5421a94d939f717c6b0b0
出典データセット: uspto-grants-1997_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05677305

反応式

参加物

反応物 3

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

関連ノート