2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one → 2-Bromo-4,6-dichloro-1-indanone
反応式
[Br:1]C1CC2C(=CC=CC=2F)C1=O.[Cl:13][C:14]1[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]2[C:15]=1[CH2:16][CH2:17][C:18]2=[O:24]>[Cu](Br)Br.O1CCOCC1>[Br:1][CH:17]1[CH2:16][C:15]2[C:19](=[CH:20][C:21]([Cl:23])=[CH:22][C:14]=2[Cl:13])[C:18]1=[O:24]参加物
5
実験手順
The 2-bromo-4,6-dichloro-1-indanone is prepared as in Example 14 for the preparation of 2-bromo-4-fluoro-1-indanone but starting with 21.6 g of 4,6-dichloro-1-indanone, 63.56 g of copper bromide and 690 ml of dioxane. 14.5 g of 2-bromo-4,6-dichloro-1-indanone are obtained which melt at 80° C.
出典と根拠
- ORDレコード
- ord-fa248855844946139a2b36b84e6193f0
- 出典データセット
- uspto-grants-1997_10
- 特許番号
- US05677306
反応ノート
読み込み中…