化工社化工社 化学情報印刷レポート · 研究参考用
4-Toluenesulfonyl chloride → N-Benzyl-3,4-dimethoxyamphetamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | 3,4-Dimethoxy-alpha-methylbenzeneethanol | HCID 89187 | — |
| 生成物 | N-Benzyl-3,4-dimethoxyamphetamine | HCID 410200 | — |
反応手順
The 1-(3,4-dimethoxyphenyl)-2-propanol obtained above was subjected to sulfonylation by p-toluenesulfonyl chloride and reacted with benzylamine to give N-benzyl-3,4-dimethoxyamphetamine. The resultant compound was converted into 3,4-dimethoxyamphetamine by hydrogenation decomposition under hydrogen atmosphere with 5% Pd-C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05679557 |
| 出典データセット | uspto-grants-1997_10 |
| ORD ID | ord-23230580570741439b6da90e8ab163d9 |
| 出典メモ | uspto-grants-1997_10 |