HCID 22902236、化合物 → HCID 22902199、化合物
反応式
COC([NH:5][C:6]12[CH2:14][N:13](C(OC)=O)[CH2:12][CH:11]1[CH:10]=[CH:9][CH:8]=[CH:7]2)=O>O>[CH2:12]1[CH:11]2[C:6]([NH2:5])([CH:7]=[CH:8][CH:9]=[CH:10]2)[CH2:14][NH:13]1参加物
3
試薬・触媒・溶媒 1
実験手順
20 g of crude methyl 1-methoxycarbonylamino-8-azabicyclo[4.3.0]nona-2,4-diene-8-carboxylate are heated with 75 g (0.235 mol) of Ba(OH)2.8 H2O in 250 ml of water overnight under reflux. The BaCO3 is filtered off with suction, the filtrate is concentrated and the salt residues are boiled three times with 1,4-dioxane. The dioxane solutions are concentrated and the residue is distilled. Yield: 5 g (43.9% of theory based on Step D), boiling point: 65° C./0.2 mbar.
後処理
- filtrationThe BaCO3 is filtered off with suction
- concentrationthe filtrate is concentrated
- concentrationThe dioxane solutions are concentrated
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-8bf60291ce6f49f58192a3707e6d10fc
- 出典データセット
- uspto-grants-1997_10
- 特許番号
- US05679689
反応ノート
読み込み中…