tert-Butyl hydroperoxide → 2,6-Dichlorobenzoyl diphenylphosphine oxide

HRID 1489923ノート

反応式

HRID 1489923 の反応式
[OH:1][CH:2]([P:11](=[O:24])([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:3]1[C:8]([Cl:9])=[CH:7][CH:6]=[CH:5][C:4]=1[Cl:10].C/C(/[O-])=C/C(C)=O.C(OO)(C)(C)C>ClC1C=CC=CC=1>[Cl:10][C:4]1[CH:5]=[CH:6][CH:7]=[C:8]([Cl:9])[C:3]=1[C:2]([P:11](=[O:24])([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:1]

参加物

5

反応物 3

HCID 6410tert-Butyl hydroperoxideHCID 5460482AcetylacetonateHCID 10970858alpha-Hydroxy-(2,6-dichlorobenzyl)-diphenyl phosphine oxide

生成物 1

HCID 109816492,6-Dichlorobenzoyl diphenylphosphine oxide収率 64%

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

To 15 g (0.04 mol) of α-hydroxy-(2,6-dichorobenzyl)-diphenyl phosphine oxide and 0.4 g (1.5 mmol) of vanadyl(IV) bis-acetylacetonate in 100 g of chlorobenzene there were added 12.9 g (0.1 mol) 70 wt % strength aqueous tert-butylhydroperoxide, and the mixture was kept at 70° C. for 5 h. The product was isolated by crystallization. Yield: 64%, mp 156°-158° C.

後処理

  1. customThe product was isolated by crystallization

出典と根拠

ORDレコード
ord-33bebe2b55134f9dba1197f54d164f89
出典データセット
uspto-grants-1997_10
特許番号
US05679863

反応ノート

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