関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | (Ethylthio)benzene | HCID 12144 | — |
| 試薬 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 試薬 | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| 触媒 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 溶媒 | P-Xylene | HCID 7809 | — |
| 生成物 | 2-(2-(Ethylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 123787969 | 72% |
反応手順
Ligand 3f: The mixture of product (95 mg, 72% yield, ortho/meta + para = >30); ortho-borylated product 4b was obtained by further purification of the crude mixture by GPC (89 mg, 67% yield), white solid (mp. 48-50 oC)
情報源と証拠
| DOI | 10.1002/anie.201610041 |
|---|
| 出典データセット | Borylation dataset from Roche |
|---|
| ORD ID | ord-b26c7059a55f4ed08e56318eb7eb563c |
|---|
| 出典メモ | Borylation dataset from Roche |
|---|
