関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Phenylisoquinoline | HCID 137882 | — |
| 試薬 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 試薬 | 4,4,5,5-Tetramethyl[1,3,2]dioxaborolane | HCID 2734768 | — |
| 試薬 | N,N-Dibenzyl-N'-(pyridin-2-ylmethylene)hydrazine | HCID 67601456 | — |
| 触媒 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]isoquinoline | HCID 140786443 | 78% |
反応手順
Following the general procedure, precipitation from the reaction crude with hexane, trituration and filtration afforded 9n (132 mg, 80 %) as a light brown solid.
情報源と証拠
| DOI | 10.1002/anie.201104544 |
|---|
| 出典データセット | Borylation dataset from Roche |
|---|
| ORD ID | ord-9cd5a8a6d6f84ea8b68e2222fc75d190 |
|---|
| 出典メモ | Borylation dataset from Roche |
|---|
