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Isobutyronitrile → N-(2-morpholinophenyl)isobutyramidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isobutyronitrile | HCID 6559 | — |
| 反応物 | 2-Morpholinoaniline | HCID 735756 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 生成物 | N-(2-morpholinophenyl)isobutyramidine | HCID 178449872 | — |
反応手順
A mixture of 4-(2-aminophenyl)morpholine (5.34 g), isobutyronitrile (6 g) and anhydrous aluminium chloride (12 g) was heated at 160°-170° C. for 6 hours to give N-(2-morpholinophenyl)isobutyramidine (m.p. 138° C.) which was recrystallised from a 1:1 mixture of ethylacetate and hexane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05373008 |
| 出典データセット | uspto-grants-1994_12 |
| ORD ID | ord-dc2260a1437242ecacff361fbb87fda7 |
| 出典メモ | uspto-grants-1994_12 |