1,3-Dimethyl-2-imidazolidinone → 4-[2-(1,3-Dimethyl-2-imidazolidinylideneamino)phenyl]morpholine

HRID 1492195

反応式

HRID 1492195 の反応式
[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH3:7])[C:3]1=O.[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>C1C=CC=CC=1.P(Cl)(Cl)(Cl)=O>[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH3:7])[C:3]1=[N:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1

参加物

5

反応物 2

HCID 66611,3-Dimethyl-2-imidazolidinoneHCID 7357562-Morpholinoaniline

生成物 1

HCID 537898944-[2-(1,3-Dimethyl-2-imidazolidinylideneamino)phenyl]morpholine

試薬・触媒・溶媒 2

HCID 241Benzene溶媒2 回HCID 24813Phosphorus oxychloride溶媒

実験手順

A mixture of 1,3-dimethyl-2-imidazolidinone (7 g) in benzene (45 ml), phosphorus oxychloride (6 ml) and 4-(2-aminophenyl)morpholine (8.5 g) in benzene (30 ml) was heated for 30 hours at 65°-70° C. The product was recrystallised from hexane to give 4-[2-(1,3-dimethyl-2-imidazolidinylideneamino)phenyl]morpholine (m.p. 133°-134° C.).

後処理

  1. temperaturewas heated for 30 hours at 65°-70° C
  2. customThe product was recrystallised from hexane

出典と根拠

ORDレコード
ord-a5925cd9cc6644fc9c71ff3a7afe706b
出典データセット
uspto-grants-1994_12
特許番号
US05373008

関連ノート

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