Sodium methanethiolate → HCID 12882536、化合物
反応式
F[C:2]1[CH:11]=[C:10]([S:12][CH3:13])[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[CH3:14][S-:15].[Na+]>CN(C)C=O>[CH3:14][S:15][C:2]1[CH:11]=[C:10]([S:12][CH3:13])[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5]参加物
4
反応条件
- 温度
- 50 °C
実験手順
A mixture of methyl 2-fluoro-4-methylsulphenylbenzoate (4.1 g), sodium thiomethoxide (1.48 g) and N,N-dimethylformamide (16 ml) was stirred at 50° C. for 18 hours, poured onto water and extracted (ethyl acetate). The extract was washed (water), dried (magnesium sulphate) and evaporated to give methyl 2-methylsulphenyl-4-methylsulphenylbenzoate (2.09 g) as an orange oil, NMR (CDCl3) 2.0 (s,3H), 2.4 (s,3H), 3.65 (s,2H), 3.9 (s,3H), 7.05 (dd,1H), 7.15 (d,1H), 7.9 (d,1H).
後処理
- additionpoured onto water
- extractionextracted (ethyl acetate)
- washThe extract was washed (water)
- dry with materialdried (magnesium sulphate)
- customevaporated
出典と根拠
- ORDレコード
- ord-917cc09ac33a4fe0bfeb802fc6b94611
- 出典データセット
- uspto-grants-1994_12
- 特許番号
- US05374606
反応ノート
読み込み中…