HCID 54069555、化合物 → HCID 18950751、化合物

HRID 1492557ノート

反応式

HRID 1492557 の反応式
[O:1]=[C:2]([C:18]1[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=1)[CH:3]=[CH:4][C:5]1[CH:17]=[CH:16][C:8]([O:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:7][CH:6]=1>C(O)C.[H][H]>[O:1]=[C:2]([C:18]1[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=1)[CH2:3][CH2:4][C:5]1[CH:17]=[CH:16][C:8]([O:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:7][CH:6]=1

参加物

4

反応物 1

HCID 54069555HCID 54069555、化合物

生成物 1

HCID 18950751HCID 18950751、化合物収率 50.3%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 178418361HCID 178418361、化合物溶媒

実験手順

Ethyl 4-[3-oxo-3-(3-pyridyl)-1-propenyl]phenoxyacetate (3.85 g) and 1.15 g of 10% Pd--C were suspended in 300 ml of ethanol, and stirred in hydrogen atmosphere at ambient temperature and pressure for three hours. The reaction mixture was filtered, and the filtrate was evaporated under reduced pressure. The residue obtained was subjected to chromatography on a silica gel column, and from a fraction eluted with methylene chloride was obtained 1.95 g of ethyl 4-[3-oxo-3-(3-pyridyl)propyl]phenoxyacetate.

後処理

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated under reduced pressure
  3. customThe residue obtained
  4. washfrom a fraction eluted with methylene chloride

出典と根拠

ORDレコード
ord-d2031f836e2f4531a4171913536e534b
出典データセット
uspto-grants-1994_12
特許番号
US05374641

反応ノート

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