化工社化工社 化学情報印刷レポート · 研究参考用
N-(oxan-4-ylidene)hydroxylamine → tetrahydropyran-4-one O-{4-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]-alpha-methylbenzyl}oxime
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(oxan-4-ylidene)hydroxylamine | HCID 12298558 | — |
| 反応物 | 4-{3-[4-(1-Chloroethyl)phenylthio]-5-fluorophenyl}-4-methoxytetrahydropyran | HCID 19379931 | — |
| 生成物 | tetrahydropyran-4-one O-{4-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]-alpha-methylbenzyl}oxime | HCID 19379937 | 74% |
反応手順
Using an analogous procedure to that described in Example 1, tetrahydropyran-4-one oxime was reacted with 4-{3-[4-(1-chloroethyl)phenylthio]-5-fluorophenyl}-4-methoxytetrahydropyran to give tetrahydropyran-4-one O-{4-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio]-α-methylbenzyl}oxime as an oil in 74% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05376680 |
| 出典データセット | uspto-grants-1994_12 |
| ORD ID | ord-68ce202b88454e78bf074fbdfe5a1f4e |
| 出典メモ | uspto-grants-1994_12 |