Carbon Tetrachloride → HCID 14999113、化合物
反応式
C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.O[CH2:21][CH2:22][N:23]1[C:27](=[O:28])[CH:26]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[S:25][CH:24]1[C:38]1[CH:39]=[N:40][CH:41]=[CH:42][CH:43]=1.C(Cl)(Cl)(Cl)[Cl:45]>>[Cl:45][CH2:21][CH2:22][N:23]1[C:27](=[O:28])[CH:26]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[S:25][CH:24]1[C:38]1[CH:39]=[N:40][CH:41]=[CH:42][CH:43]=1参加物
4
実験手順
Triphenylphosphine (3.44 g, 13 mmol) was added to a mixture of 3-(2-hydroxyethyl)-5-(n-nonyl)-2-(3-pyridyl)thiazolidin-4-one (3.49 g, 10 mmol) and carbon tetrachloride (20 ml) with stirring at room temperature. Then the mixture was refluxed with stirring for 2.5 hours. The product mixture was cooled and filtered to remove the formed crystals. The filtrate was concentrated and chromatographed, giving the cis-isomer (0.55 g) and trans-isomer (1.46 g) of the title compound and a mixture of two isomers (0.94 g) (total 2.95 g, 80% yield).