Benzoylhydrazine → HCID 54014022、化合物

HRID 1493692ノート

反応式

HRID 1493692 の反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([CH2:9][CH2:10][CH2:11][CH3:12])=O)=[CH:3][CH:2]=1.[C:13]([NH:21][NH2:22])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:22][NH:21][C:13](=[O:20])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:9][CH2:10][CH2:11][CH3:12])=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 11955BenzoylhydrazineHCID 743441-Pentanone, 1-(4-pyridyl)-

生成物 1

HCID 54014022HCID 54014022、化合物収率 77%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 5.97 gm (0.0366 mole) of n-butyl 4-pyridinyl ketone, 5.45 gm (0.04 mole) of benzoic acid hydrazide and 100 ml of absolute ethanol is refluxed 4.5 hr. The hot solution is filtered. The filtrate is diluted with water to the cloud point, cooled to room temperature and chilled. The solids which deposit are collected, washed with water and dried to yield 7.89 gm (77%) of the title compound having a melting point of 142.1° C.

後処理

  1. temperatureis refluxed 4.5 hr
  2. filtrationThe hot solution is filtered
  3. additionThe filtrate is diluted with water to the cloud point
  4. temperaturechilled
  5. customThe solids which deposit are collected
  6. washwashed with water
  7. customdried

出典と根拠

ORDレコード
ord-490ddb93cf16437facd72c112f21f69f
出典データセット
uspto-grants-1991_06
特許番号
US05023334

反応ノート

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