化工社化工社 化学情報印刷レポート · 研究参考用
Diethyl Malonate → Diethyl 2-pent-4-enylpropanedioate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Malonate | HCID 7761 | — |
| 反応物 | 1-Pentene, 5-bromo- | HCID 70704 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Diethyl 2-pent-4-enylpropanedioate | HCID 361718 | — |
反応手順
To 300 mL of ethanol are added 5 g of sodium spheres and after a clear solution is obtained, 32.1 g of diethyl malonate is added in one portion. After 1 hour at room temperature, 15 g of 5-bromopent-1-ene is added and the reaction mixture is stirred at room temperature for 16 hours. The reaction mixture is evaporated to dryness and the residue is distilled under high vacuum to obtain diethyl pent-4-enylmalonate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05025025 |
| 出典データセット | uspto-grants-1991_06 |
| ORD ID | ord-c794d2b781404eb9bf90b823205e2353 |
| 出典メモ | uspto-grants-1991_06 |