Ammonia → 1-carbamoylmethylquinoxaline-2,3(1H,4H)-dione

HRID 1494350

反応式

HRID 1494350 の反応式
C[O:2][C:3]([CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][C:8](=[O:16])[C:7]1=[O:17])=O.[NH3:18]>>[C:3]([CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][C:8](=[O:16])[C:7]1=[O:17])(=[O:2])[NH2:18]

参加物

3

反応物 2

HCID 222AmmoniaHCID 129386651-methoxycarbonylmethylquinoxaline-2,3(1H,4H)-dione

生成物 1

HCID 198278111-carbamoylmethylquinoxaline-2,3(1H,4H)-dione収率 32%

実験手順

A mixture of 0.17 g (0.7 mmol) 1-methoxycarbonylmethylquinoxaline-2,3(1H,4H)-dione and 10 ml 25% aqueous ammonia was stirred for 18 h. The product was filtered off and washed with cold water to give 0.05 g (32%) 1-carbamoylmethylquinoxaline-2,3(1H,4H)-dione. M.p. >300° C. MS m/c: 219 (M+, 40%), 119 (100%).

後処理

  1. filtrationThe product was filtered off
  2. washwashed with cold water

出典と根拠

ORDレコード
ord-be4335eda0724bfebaf523f5a7b2add7
出典データセット
uspto-grants-1991_06
特許番号
US05026704

関連ノート

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