Swainsonine → (1S,2R,6R,7S)-1,2,6,7-tetrahydroxypyrrolizidine
反応式
[CH2:1]1[CH2:9][N:8]2[C@@H:4]([C@H:5]([OH:11])[C@H:6]([OH:10])[CH2:7]2)[C@H:3]([OH:12])C1.C1(=O)O[C@@H]([C@@H]([C@@H](CO)O)O)[C@H](O)[C@@H]1[OH:15]>>[OH:12][C@H:3]1[CH:4]2[N:8]([CH2:7][C@@H:6]([OH:10])[C@H:5]2[OH:11])[CH2:9][C@H:1]1[OH:15]参加物
3
実験手順
The tetrahydroxypyrrolizidone (1) is an analogue of 1,8-diepiswainsonine. A similar analogue of swainsonine can be made by analogous methods starting with D-glycero-D-talo-heptono-1,4-lactone to produce the novel (1S, 2R, 6R, 7S)-1,2,6,7-tetrahydroxypyrrolizidine.
出典と根拠
- ORDレコード
- ord-88e800e4448042938511a78f3389dedb
- 出典データセット
- uspto-grants-1991_06
- 特許番号
- US05026870
反応ノート
読み込み中…