Tert-butyl 4-(4-amino-3-methoxyphenyl)piperazine-1-carboxylate → 1-(4-(3-(Difluoromethoxy)-4-(5-fluoro-2-(2-methoxy-4-(piperazin-1-yl)phenylamino)pyrimidin-4-ylamino)phenyl)piperazin-1-yl)ethanone
反応式
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([N:15]3[CH2:20][CH2:19][N:18]([C:21](=[O:23])[CH3:22])[CH2:17][CH2:16]3)=[CH:11][C:10]=2[O:24][CH:25]([F:27])[F:26])[C:5]([F:28])=[CH:4][N:3]=1.C(OC([N:36]1[CH2:41][CH2:40][N:39]([C:42]2[CH:47]=[CH:46][C:45]([NH2:48])=[C:44]([O:49][CH3:50])[CH:43]=2)[CH2:38][CH2:37]1)=O)(C)(C)C>C(OC(O)C)C.Cl>[F:26][CH:25]([F:27])[O:24][C:10]1[CH:11]=[C:12]([N:15]2[CH2:20][CH2:19][N:18]([C:21](=[O:23])[CH3:22])[CH2:17][CH2:16]2)[CH:13]=[CH:14][C:9]=1[NH:8][C:6]1[C:5]([F:28])=[CH:4][N:3]=[C:2]([NH:48][C:45]2[CH:46]=[CH:47][C:42]([N:39]3[CH2:38][CH2:37][NH:36][CH2:41][CH2:40]3)=[CH:43][C:44]=2[O:49][CH3:50])[N:7]=1参加物
4
