Pyrimidine, 2-ethynyl-4-methoxy- (9CI) → HCID 71743828、化合物
反応式
[F:1][C:2]1[C:3]([O:14][CH3:15])=[N:4][C:5]([C:8]#[C:9][Si](C)(C)C)=[N:6][CH:7]=1.C(C1N=C(OC)C=CN=1)#C>>[C:8]([C:5]1[N:4]=[C:3]([O:14][CH3:15])[C:2]([F:1])=[CH:7][N:6]=1)#[CH:9]参加物
3
実験手順
Obtained (82%) from 5-fluoro-4-methoxy-2-((trimethylsilyl)ethynyl)pyrimidine (Preparation 16b) following the experimental procedure as described in Preparation 1b followed by purification by flash chromatography (99:1 dichloromethane/methanol).
後処理
- customfollowed by purification by flash chromatography (99:1 dichloromethane/methanol)
出典と根拠
- ORDレコード
- ord-8478145a147f4cda96e93b0888abb220
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09206183B2
反応ノート
読み込み中…