L-(+)-Cysteine → HCID 57312911、化合物
反応式
[NH2:1][C@H:2]([C:5]([OH:7])=[O:6])[CH2:3][SH:4].[C:8]([O:12][CH2:13][CH3:14])(=[O:11])[CH:9]=O>O>[CH3:14][CH2:13][O:12][C:8]([CH:9]1[NH:1][CH:2]([C:5]([OH:7])=[O:6])[CH2:3][S:4]1)=[O:11]参加物
4
実験手順
L-Cysteine (60.4 g, 0.50 mmol) and ethyl glyoxylate (polymer, 47% toluene solution, 50.9 g, 0.234 mol) were added to water (150 ml), and the mixture was stirred at room temperature for 50 hours. The obtained solution was concentrated under reduced pressure, and the precipitated solid was collected by filtration. The obtained white solid (about 40 g) was suspended in water (100 ml), and the suspension was stirred for 16 hours at slurry state. The white crystals were collected by filtration, and dried under reduced pressure to give thiazolidine-2,4-dicarboxylic acid 2-ethyl ester as a white solid (30.08 g).
後処理
- concentrationThe obtained solution was concentrated under reduced pressure
- filtrationthe precipitated solid was collected by filtration
- stirringthe suspension was stirred for 16 hours at slurry state
- filtrationThe white crystals were collected by filtration
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-12434506e2874cdbb5e2421ef6840927
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09212154B2
反応ノート
読み込み中…