4-(2-Ethoxycarbonyl-3-oxobutyl)biphenyl → HCID 178423484、化合物

HRID 1503229

反応式

HRID 1503229 の反応式
[NH:1]([C:3]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([CH3:12])=[CH:11][C:5]=2[N:4]=1)[NH2:2].[C:13]([CH:16]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[CH:25][CH:24]=1)[C:17](OCC)=[O:18])(=O)[CH3:14]>>[CH3:14][C:13]1[C:16]([CH2:22][C:23]2[CH:28]=[CH:27][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:25][CH:24]=2)=[C:17]([OH:18])[N:1]([C:3]2[NH:7][C:6]3[CH:8]=[CH:9][C:10]([CH3:12])=[CH:11][C:5]=3[N:4]=2)[N:2]=1

参加物

3

反応物 2

HCID 133237014-(2-Ethoxycarbonyl-3-oxobutyl)biphenylHCID 178423496HCID 178423496、化合物

生成物 1

HCID 178423484HCID 178423484、化合物

実験手順

Using 2-hydrazino-5-methyl-1H-benzimidazole (4) obtained in Example 1, step 3 and ethyl 2-acetyl-3-(4-phenylphenyl)propanoate (33), and by a method similar to that in Example 1, step 4, 3-methyl-1-(5-methyl-1H-benzimidazol-2-yl)-4-[(4-phenylphenyl)methyl]-1H-pyrazol-5-ol (34) was obtained.

出典と根拠

ORDレコード
ord-082c41c1c63f4d6db28ddf6fc441dae7
出典データセット
uspto-grants-2015_12
特許番号
US09212169B2

関連ノート

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