化工社化工社 化学情報印刷レポート · 研究参考用
4-tert-Butylcyclohexanone → 1-[4-(Tert-butyl)-1-cyclohexen-1-YL]pyrrolidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-tert-Butylcyclohexanone | HCID 7392 | — |
| 反応物 | Pyrrolidine | HCID 31268 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-[4-(Tert-butyl)-1-cyclohexen-1-YL]pyrrolidine | HCID 107232 | — |
反応手順
A 50 mL round-bottomed flask containing 4-tert-butylcyclohexanone (6.01 gm) in anhydrous toluene (20 mL) was fitted with a Dean-Stark trap containing 3A molecular sieves, reflux condenser and a heating mantle. Pyrrolidine (6.00 mL) was added, and the solution heated to reflux for 18 hr. The solvent was evaporated and the crude product was used directly for the next reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09216966B2 |
| 出典データセット | uspto-grants-2015_12 |
| ORD ID | ord-bcf3b8f806d74b62bb2d057e7b5ce976 |
| 出典メモ | uspto-grants-2015_12 |