Ammonia → HCID 90405643、化合物
反応式
[CH3:1][O:2][C:3]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:4]=1[CH:5]=[C:6]([C:13]([O:15]C)=O)[NH:7]2.[NH3:17]>CO>[CH3:1][O:2][C:3]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:4]=1[CH:5]=[C:6]([C:13]([NH2:17])=[O:15])[NH:7]2参加物
4
実験手順
80 mg of methyl 4-methoxy-5-methyl-1H-indole-2-carboxylate (0.39 mmol) was heated at 80 degrees in a sealed tube with 1 mL of 7M ammonia in methanol. After one week reaction the solvent evaporated to produce 79 mg of 4-methoxy-5-methyl-1H-indole-2-carboxamide that was used without purification in the next step.
後処理
- customAfter one week reaction the solvent
- customevaporated
出典と根拠
- ORDレコード
- ord-7981d7b370454baf9dc58b1830e07515
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09216993B2
反応ノート
読み込み中…