Carbon Tetrachloride → Ethyl 2-chloro-2-(o-tolylimino)acetate

HRID 1506628ノート

反応式

HRID 1506628 の反応式
O=[C:2]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Cl)(Cl)(Cl)[Cl:36]>>[Cl:36][C:2](=[N:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4]

参加物

4

反応物 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 366755Ethyl [(2-methylphenyl)amino](oxo)acetate

生成物 1

HCID 90280270Ethyl 2-chloro-2-(o-tolylimino)acetate

実験手順

The suspension of ethyl 2-oxo-2-(o-tolylamino)acetate (2.0 g, 10 mmol) and triphenylphosphine (4.0 g, 15 mmol) in carbon tetrachloride (150 mL) was refluxed overnight. The reaction was cooled down and filtered. The filtrate was collected and concentrated and used it without further purification. MS (m/z) 226 [M+H]+.

後処理

  1. temperaturewas refluxed overnight
  2. temperatureThe reaction was cooled down
  3. filtrationfiltered
  4. customThe filtrate was collected
  5. concentrationconcentrated
  6. customwithout further purification

出典と根拠

ORDレコード
ord-e2541b6eee964802a631689e192c3bde
出典データセット
uspto-grants-2015_12
特許番号
US09220710B2

反応ノート

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