(NZ)-N-[[2-(4-chlorophenyl)-1,3-oxazol-5-yl]methylidene]-2-methylpropane-2-sulfinamide → 1-(2-(4-Chlorophenyl)oxazol-5-yl)-2-(3,5-difluorophenyl)ethanamine hydrochloride
反応式
[F:1][C:2]1[CH:3]=[C:4]([CH2:9][C@@H:10]([C:12]2N(C3C=CC(OC)=CC=3)C=CN=2)[NH2:11])[CH:5]=[C:6]([F:8])[CH:7]=1.[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[O:33]C(/C=N\S(C(C)(C)C)=O)=[CH:35][N:36]=2)=[CH:28][CH:27]=1>>[ClH:25].[Cl:25][C:26]1[CH:27]=[CH:28][C:29]([C:32]2[O:33][C:12]([CH:10]([NH2:11])[CH2:9][C:4]3[CH:5]=[C:6]([F:8])[CH:7]=[C:2]([F:1])[CH:3]=3)=[CH:35][N:36]=2)=[CH:30][CH:31]=1参加物
3
実験手順
The title compound was prepared according to the method presented for the synthesis of compound 5E of Example 5 utilizing 19D. MS (m/z) 335.2 [M+H]+.
出典と根拠
- ORDレコード
- ord-fe89d246894a4f5686e66e8d8443319d
- 出典データセット
- uspto-grants-2015_12
- DOI