N-(1-(5-(4-chlorophenyl)oxazol-4-yl)-2-(3,5-difluorophenyl)ethyl)-2-methylpropane-2-sulfinamide → 1-(5-(4-Chlorophenyl)oxazol-4-yl)-2-(3,5-difluorophenyl)ethanamine hydrochloride
反応式
FC1C=C(C[C@@H](C2N(C3C=CC(OC)=CC=3)C=CN=2)N)C=C(F)C=1.[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[O:36][CH:35]=[N:34][C:33]=2[CH:37]([NH:47]S(C(C)(C)C)=O)[CH2:38][C:39]2[CH:44]=[C:43]([F:45])[CH:42]=[C:41]([F:46])[CH:40]=2)=[CH:28][CH:27]=1>>[ClH:25].[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]2[O:36][CH:35]=[N:34][C:33]=2[CH:37]([NH2:47])[CH2:38][C:39]2[CH:44]=[C:43]([F:45])[CH:42]=[C:41]([F:46])[CH:40]=2)=[CH:28][CH:27]=1参加物
3
反応物 2
生成物 1
実験手順
The title compound was prepared according to the method presented for the synthesis of compound 5E of Example 5 utilizing 33F. MS (m/z) 335.1 [M+H]+.
出典と根拠
- ORDレコード
- ord-e70c488c2009410d80351ee283389962
- 出典データセット
- uspto-grants-2015_12