Ethyl 2-chloro-4-ethoxy-6-methylpyridine-3-carboxylate → 3-Hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

反応式

[CH2:1]([O:3][C:4]([C:6]1[O:14]C2N=NC=CC=2C=1O)=[O:5])[CH3:2].C(O[C:19](=[O:31])[C:20]1[C:25]([O:26][CH2:27][CH3:28])=[CH:24][C:23]([CH3:29])=[N:22][C:21]=1Cl)C>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:21]2=[N:22][C:23]([CH3:29])=[CH:24][C:25]([O:26][CH2:27][CH3:28])=[C:20]2[C:19]=1[OH:31])=[O:5])[CH3:2]

参加物

反応物 2

HCID 52911135Ethyl 2-chloro-4-ethoxy-6-methylpyridine-3-carboxylate

HCID 71239586HCID 71239586、化合物

生成物 1

HCID 712393813-Hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

実験手順

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-4-ethoxy-6-methylnicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

後処理

customThis compound was prepared

出典と根拠

ORDレコード: ord-1ba7b0ee80be48ccb086a01ade0ed016
出典データセット: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09221832B2

反応ノート

読み込み中…

参加物