2-Chloro-4-methoxy-6-methylnicotinic acid ethyl ester → 3-Hydroxy-4-methoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

HRID 1508255ノート

反応式

HRID 1508255 の反応式
[CH2:1]([O:3][C:4]([C:6]1[O:14]C2N=NC=CC=2C=1O)=[O:5])[CH3:2].C(O[C:19](=[O:30])[C:20]1[C:25]([O:26][CH3:27])=[CH:24][C:23]([CH3:28])=[N:22][C:21]=1Cl)C>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:21]2=[N:22][C:23]([CH3:28])=[CH:24][C:25]([O:26][CH3:27])=[C:20]2[C:19]=1[OH:30])=[O:5])[CH3:2]

参加物

3

反応物 2

HCID 139336422-Chloro-4-methoxy-6-methylnicotinic acid ethyl esterHCID 71239586HCID 71239586、化合物

生成物 1

HCID 712393923-Hydroxy-4-methoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

実験手順

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-4-methoxy-6-methylnicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

後処理

  1. customThis compound was prepared

出典と根拠

ORDレコード
ord-d22ceab280c049e79fb3c0c86181a327
出典データセット
uspto-grants-2015_12
特許番号
US09221832B2

反応ノート

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